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The wound healing mechanism involves multiple coordinated processes: recruitment of macrophages and mast cells, stimulation of glycosaminoglycan synthesis (particularly dermatan sulfate), promotion of nerve growth factor expression, and enhancement of vascular endothelial growth factor (VEGF) secretion
Imaging studies offer the most objective assessment but add cost and complexity
Gastroenterology 77:761767, 1979 Schmidt KL, Miller TA: Cytoprotection: Fact or fancy
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