L., Kjr, L
C (101 MHz, MeOD): 174.49 (C), 172.86 (C), 172.60 (C), 171.54 (C), 171.49 (C), 161.66 (q, J = 36.3 Hz, CF 3 C O), 135.79 (t, J = 24.4 Hz, CH), 134.39 (td, J = 25.0, 9.9 Hz, CH), 131.04 (td, J = 25.2, 12.6 Hz, CH), 119.7o (d, J = 86.2 Hz, C), 53.79 (CH), 53.52 (CH), 43.42 (CH 2 ), 41.83 (CH 2 ), 40.74 (CH 2 ), 40.24 (CH 2 ), 32.37 (CH 2 ), 29.46 (CH 2 ), 28.74 (d, J = 16.8 Hz, CH), 27.03 (CH 2 ), 23.13 (d, = J 4.3 Hz, CH), 22.67 (d, J = 51.3 Hz, CH)
It is hypothesized that Ipamorelin potentially increased the weights of fat pads in relation to body weight, which appeared to lead to an increase in relative body fat as quantified by dual energy X-ray absorptiometry (DEXA)
CagriSema-style escalation starts at 0.25 mg per week with semaglutide and steps up every 4 weeks (0.5, 1.0, 1.7, 2.4 mg) over 16 weeks