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Because we could observe significant numbers of Ki-67+ matrix keratinocytes even in NTAPP-untreated hair bulbs, the effect of NTAPP might be obscured in ex vivo conditions in which exogenous factors stimulating hair growth may exist
Histone deacetylases including SIRT1, interact with STAT3 and negatively regulate its transcriptional activity by deacetylating critical lysine residues (Nie et al., 2009)
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