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But six weeks is barely the opening act of a medication that requires months or years to deliver its full effect, needs to be taken indefinitely to maintain results, and doesnt work for a meaningful proportion of people who try it
Some researchers find their optimal response at 8mg
Constipation builds over weeks
For patients who are newer to GLP-1 therapy or who want to start with semaglutide before potentially switching from tirzepatide to semaglutide or vice versa, this provides flexibility
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