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Peptides can sometimes adhere to the plastic of the syringe over time, which can reduce the effective dose being administered
Because ongoing efforts to slow the progression of Alzheimers have largely been disappointing, even a minor success would provide a rare glimmer of hope for people in the early stages of the condition
This reluctance is likely to be at least partially attributable to the fact that, until recently, all GLP-1RAs were available as subcutaneous (s.c.) injections, given twice daily (exenatide [13]), once daily (lixisenatide [14] and liraglutide [15]), or once weekly (semaglutide [16], dulaglutide [17], and exenatide extended release [18]), a route that may be less preferable to some patients compared with oral administration [1, 19]
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