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These effects often relate to slowed gastric emptying and can be managed with smaller bites, slower eating, reduced fat intake during titration, and adequate hydration

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James LP, Simpson PM, Capperelli E, Roberts DW, Hinson JA, Davern TJ, Lee WM: Pharmacokinetics of acetaminophen-protein adducts in adults with acetaminophen overdose and acute liver failure

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