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This interaction reduces inhibitory binding between caveolin-1 and endothelial nitric oxide synthase, allowing increased enzyme activity and nitric oxide production in endothelial cells

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The compound has been characterised across multiple research streams covering NNMT enzyme inhibition mechanism, adipocyte and obesity research, methyl-donor pool conservation, NAD+ pathway research, cancer-research framings (NNMT overexpression in tumours)