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In terms of its mechanism of action, it works by stimulating the hormone receptors for GIP, or glucose-dependent insulinotropic polypeptide, and GLP-1, or glucagon-like peptide-1
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Probiotic breakthrough: Clostridium butyricum improved the intestinal SCFAs content, digestive enzymes and antioxidant activities, gut morphology and microbiota composition of largemouth bass
While its common side effects (such as gastrointestinal discomfort and fishy odor) are reversible and dose-dependent, chronic administration poses a specific risk because LC is metabolized into trimethylamine-N-oxidase (TMAO)a pro-atherogenic metabolite that paradoxically counteracts its cardioprotective role (Elantary and Othman, 2024)
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