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For dental patients undergoing deep sedation or general anaesthesia, best practices include holding daily GLP-1 agonists on the day of procedure and weekly GLP-1 agonists a week prior to procedure, and adhering to or extending the current ASA fasting guidelines, with the possibility of an addition period of a clear fluid diet ahead of the recommended fasting period
GLP-1 receptor agonists: Do not bypass the intestine Do not remove absorptive surface area Do not directly inhibit nutrient transporters Proceed to intake-based assessment
This strategy has fueled optimism because exatecan delivers strong antitumor activity at very low concentrations when linked to a tumor-specific antibody
Understanding the mechanism matters because it determines what to expect and when
