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In clinical pharmacology trials assessing the effect of tirzepatide 1.0 mg on the absorption of co-administered oral medications at steady state, no clinically relevant drug-drug interactions with tirzepatide were observed based on the evaluated medications
Fasting glucose decreased significantly in participants with pre-diabetes or type 2 diabetes at baseline, aligning with the GLP-1R and GIPR incretin components [1, 7]
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