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ER stress-driven B-cell differentiation and autoantibody production in SLE Autoantibodies associated with SLE can exacerbate ER stress and activate the ER stress response
References Neelakantan H, Vance V, Wetzel MD, et al
It receives raw materials and has to synthesise GSH from scratch, which is an energy-dependent process limited by cysteine availability and the rate-limiting enzyme gamma-glutamylcysteine synthetase
Frontiers in Medicine, 10
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