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Artificial erythrocytes, built from lipid membranes and loaded with hemoglobin or functional enzymes, are designed to closely mimic the structure and function of natural red cells (Liang et al., 2021
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Risk of bias was assessed for these trials using the Cochrane Risk of Bias 2 tool, and domains such as randomization, blinding, and incomplete outcome data were considered when interpreting the pooled estimates
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