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Moreover, IGF-1 released by the tumor microenvironment supported the development of drug resistance by sustaining the prompt regrowth of resistant tumor and by driving the remodeling of the tumor vasculature through activation of IGF-1R signaling on endothelial cells in a xenograft mouse model of melanoma (39)
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Semax is a synthetic peptide that has been widely studied in research environments for its potential interaction with neurological pathways and neurochemical signaling processes
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