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Adjustment Criteria: Decisions on treatment changes depend on the initial deficiency level, neurological symptoms, and how well the patient responds
For example, tryptophan metabolism via the kynurenine pathway has been extensively studied in PD, and significant alterations in the metabolites involved have been demonstrated, suggesting an imbalance toward neurotoxic and proinflammatory compounds
Or maybe you just got a shipment of lyophilized somatropin and you want to know whether it is safe for the next two years or the next two weeks
The two protocols address different systems and can run concurrently
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