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GLP-1 Receptor Agonists Related to Body Contouring Surgery The rapid and significant weight loss induced by GLP-1 RAs results in substantial depletion of subcutaneous fat and loss of skin elasticity, leading to pronounced skin laxity and body contour deformities
Cardiovascular outcome studies Although multiple clinical trials evaluating cardiovascular events associated with GLP-1 RA use as the primary outcome are currently ongoing (Table 1), abundant non-primary outcome data are available from many clinical trials on the efficacy of GLP-1 RAs marketed earlier, such as exenatide (DURATION studies) and liraglutide (LEAD studies)
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