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Researchers examined data from 227,866 people between 2006 and 2023 and found that those taking semaglutide experienced 36 percent fewer alcohol-related hospital visits compared to those not taking the medication

Together these effects have been shown to reduce glycemia and improve metabolic associated steatotic liver disease [18, 44]

Genetic Predisposition and Peptide Pathway Sensitivity Genetic variation in GLP-1 receptor signaling glucose-dependent insulinotropic polypeptide receptor pathways (GIPR rs1800437), and appetite regulation (MC4R rs17782313, FTO rs9939609) may influence individual dose tolerance and efficacy

Exp Mol Med 49 , e322, (2017)