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Experimental solubility assays require non-negligible amounts of material, in turn necessitating synthesis, and are difficult to run accurately in a high-throughput format
The expression of MiR-335 is modulated by lipid loading, resulting in overexpression in liver and adipose tissue of obese mice 93
This was accompanied by hypomethylation along the X chromosome and pericentromeric regions, suggesting changes in large-scale methylation patterns due to DNMT3B deficiency alter the timing of neuronal differentiation and maturation (Martins-Taylor et al., 2012)
A., Onyeaka, H., Nwonuma, C
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