Patients whose only complaint is weight and who have no secondary concerns about skin, hair, inflammation, or tissue quality are better served by optimizing their GLP-1 protocol, adding resistance training, and addressing nutrition rather than adding a peptide that doesnt directly address their primary goal
The reversible reduction of RS 2 and RSSR substrates can be catalyzed by a monothiol and/or dithiol mechanism depending on the substrate and organism 5,6,7,8
Leaky gut, dysbiosis (microbial imbalances), and small intestinal bacterial overgrowth (SIBO) can contribute to MCAS by increasing inflammation and allowing undigested food particles to trigger immune responses
Whereas, 4 weeks of progressive ladder-climbing RT (2 climbs per session at 75%, 90%, and 100% MCL) 5 times per week in a mouse model of AD lowered circulating IL-6 to levels comparable to healthy controls (Hashiguchi et al., 2020)