can i take a laxative while on tirzepatide Dosing Can Mounjaro Cause Constipation? Yes,

Having your medications in their original packaging and with a prescription label can help facilitate the process

Biopharma PEG Figure 4

According to a retrospective review comparing amphetamine-derived phentermine with phentermine-topiramate, phentermine and phentermine-topiramate in addition to diet and exercise in post-RYGB and LAGB patients induced weight loss of 6.35 kg (12.8% excess weight loss) and 3.81 kg (12.9% EWL) within 90 days, respectively [14]

This means you'll naturally eat less, which shouldn't impair methotrexate pharmacokinetics but may affect how you feel while adjusting to both medications simultaneously