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Preclinical cartilage evidence Kwon and Park 2015 in Annals of Clinical and Laboratory Science reported that intra-articular AOD-9604 plus hyaluronic acid in a rabbit knee osteoarthritis model improved cartilage histology and reduced lameness compared with hyaluronic acid alone
Measure Oral half-life Published finding 6.90 1.20 hours in rats What it means Animal oral data only
AOD-9604, a synthetic growth hormone analogue, has been studied as an investigational agent for several indications 1
includes warnings that parenteral thiamine may cause anaphylaxis and that the benzyl alcohol preservative is contraindicated in neonates due to risk of serious reactions)
