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J.LenaertsK.KiersD.Pais de BarrosDe BarrosJ.-P.Le GuernN.PlesnikJ.et al (2017)

Also, regular exercise helps preserve muscle and maintain metabolism

Primary pain in ALS includes neuropathic pain and pain due to spasticity or cramps, whereas secondary pain is mainly nociceptive and may appear as muscle weakness and atrophy progress [83]