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Katoh, T
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The present study assessed the potential hepatoprotective effects of phytic acid (PA), a natural antioxidant and iron chelator, on APAP-induced hepatotoxicity and the possible underlying mechanism through its effects on CYP2E1 gene expression, iron homeostasis, oxidative stress, and SIRT -1 expression levels
Li L, Muftuoglu M, Liu E, Ang S, Lv J, Wan X, Cai R, Chen H, Hu B, Jimenez J, Mak D, Burks J, Bdaiwi M, Banerjee P, Imahashi N, Kerbauy LN, Lu J, FLLW I, Mendt MC, l DePombo A, Daher M, Basar R, Neelapu S, Orlowski R, Andreeff M , Marin D, Champlin R, Shpall E, Rezvani K
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