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Nine-year effects of 3.7 years of intensive glycemic control on cardiovascular outcomes
This water-soluble vitamin serves as a cofactor for only two enzymes in human metabolism, but both are vital: methionine synthase (involved in DNA synthesis and methylation) and methylmalonyl-CoA mutase (essential for fatty acid metabolism and energy production)
Cell Tissue Res
16 17 18 Newly emerging indications for GLP-1 medicationsincluding heart disease, metabolic liver disease, peripheral artery disease, Alzheimers/dementia risk, and even alcohol and substance use disorders, as highlighted in a 2025 study in JAMA 19 suggest these drugs may soon play a much broader role in medicine than just treating diabetes or obesity
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