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Data extraction Information on the baseline characteristics of the samples enrolled included age, gender, proportion of patients with T2D, baseline BMI, TBWL%, waist circumference, body composition, proportion of patients achieving at least 5%, 10%, 15%, 20%, and 25% body weight reduction, remission or improvement/resolution of obesity-related complications, SAE, mortality, MACE, FPG, HbA1c, lipid profile, estimated glomerular filtration rate (eGFR), creatinine, albuminuria, mental health parameters and QoL

The result is not forced dieting

For many metabolic enzymes, filamentation and oligomerisation serve to provide new ligand binding sites, generate unique catalytic conformations, or transduce signals across multiple enzyme subunits