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Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein)

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Anesthesia & Analgesia 110(5): 1355-1359

Hyperactivated M1 alveolar macrophages are taken over by SARS-CoV-2 allowing for viral infection and spread, while M2 alveolar macrophages can degrade the virus and limit its spread (Knoll et al., 2021