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The American Association of Clinical Endocrinology (AACE) consensus algorithm positions GLP-1 receptor agonists ahead of sulfonylureas in the treatment hierarchy for patients with cardiovascular risk factors, giving prescribers a guideline-backed argument to request a step-therapy override [8]
Ochronosis was most often reported in middle-aged women (53.2%), of African descent (45.2%), Black races (55.5%), and Fitzpatrick skin types V-VI (52.4%)
Brain Res 2003
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