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Most recently, the group of Cani and Delzenne showed that prebiotic fructo-oligosaccharides (FOS) attenuate experimental hepatic steatosis, possibly by modulating the intestinal microbiota or the intestinal barrier function or both [103]

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Each is the latest step in a distinct multi-decade research lineage, and understanding those lineages explains why the two look so different despite chasing the same endpoint