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While these drugs have benefits, there is a serious risk of low blood sugar for those with type 1 diabetes who take a GLP-1 agonist together with insulin

For patients with type 2 diabetes taking semaglutide, understanding how different carbohydrates affect blood glucose remains important despite the medication's glucose-lowering effects

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In brain, the properties of GSH transport in isolated rat brain mitochondria seemed to be different from those reported previously for kidney mitochondria, as they were influenced most by inhibitors of the tricarboxylate carrier, citrate, isocitrate, and benzenyl-1,2,3-tricarboxylate (Wadey et al., 2009)