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Recommended investigations include: Full blood count with blood film examination Serum vitamin B12 level Serum folate (to exclude combined deficiency) Intrinsic factor antibodies Thyroid function tests (autoimmune association) Consider MMA and homocysteine if diagnosis uncertain and available Neurological examination should be performed in all patients, assessing for peripheral neuropathy, proprioception loss, and signs of subacute combined degeneration of the spinal cord

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At 10mg/ml concentration (50mg + 5ml water), a 50mg vial provides: 25 doses at 2mg each 50 doses at 1mg each 16-17 doses at 3mg each This typically supplies 4-8 weeks of use depending on dosing frequency and amount

Any cloudiness, discoloration, or visible particles are signs of contamination