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Extend your current dose step if: Nausea persists beyond 10 days at the current dose You are experiencing vomiting more than twice per week Diarrhea is disrupting daily activities You have lost significant amounts of food intake due to GI symptoms Your quality of life is substantially affected Stay at the current dose for an additional 2 to 4 weeks, then attempt the escalation again
[1] [2] This leads to reduced calorie consumption and subsequent weight loss
Apoptosis 26 (7-8), 371384
Some studies have also compared the effects of TCMs with classical ferroptosis inducers RSL-3 or erastin, which tend to increase the sensitivity of tumor cells to ferroptosis, resulting in mutual promotion (Table 2)
