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Tirzepatide (SURMOUNT-1) In adults with overweight or obesity (without type 2 diabetes), average weight loss over 72 weeks was 15.0% (5 mg), 19.5% (10 mg), and 20.9% (15 mg), compared with 3.1% for placebo, alongside lifestyle changes
Ozempic may contribute to an increased risk for thyroid c-cell tumors, acute pancreatitis, gallbladder disease, hypoglyceia, acute kidney injury, severe GI side effects, and an increased risk for worsening of diabetic retinopathy in people with type 2 diabetes
Insulin is also called the hormone of satiety or excess
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