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The TGF-/SMAD pathway, which zinc supports as an essential cofactor, regulates ECM deposition, aiding granulation tissue formation [325]
While OPLL may remain asymptomatic or manifest with nonspecific symptoms, even minor trauma can precipitate severe neurological deficits, including sensory and motor impairments, reflex abnormality, and urinary/fecal dysfunction
Patients should be provided with a letter from their healthcare provider or pharmacy documenting the medical necessity of carrying injection supplies
Always consult your doctor before giving this medicine to a child
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