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2022 Sep 30;31(3):217-229

Dagda et al., 2008

The resulting positive pressure differential forces liquid back through the needle tract on every subsequent draw, pulling contaminants into the vial and degrading sterility across the 28-day use window

But the direction of travel is clear: the category is contracting, the compliance requirements are tightening, and the platforms that operate with transparent legal architecture - LegitScript verification, disclosed medical group, clear compounding pharmacy structure - are the ones most likely to still be running the same program in twelve months that they're running today