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36 resistance-trained people were assigned to supplement with creatineat random between creatine monohydrate, a manufacturers recommended dose of Kre-Alkalyn, and a higher dose of Kre-Alkalyn to match the standard doses of monohydrate (a loading dose of 20g/day in the first week, then 5g/day in the following weeks)
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The death of motor neurons results in a characteristic clinical feature: spasticity, muscular weakness and atrophy, hyperreflexia, cramps, fasciculation, Babinski sign, loss of coordination, paralysis of voluntary musculature, dysphagia and difficulties in swallowing, speech and respiration (Weiduschat et al., 2014