When higher levels of acetaminophen are ingested, the livers supply of glutathione is depleted and NAPQI causes liver damage.[ref] Related article: Genetic variants that increase the risk of liver damage from acetaminophen Studies on the impacts of low glutathione levels: Glutathione levels in the body are fairly tightly regulated, and balance is key
Controlled human trials exist, but they're limited in size, focused mostly on topical cosmetic use, and usually last only a few weeks or months. That means a lot of the exciting claims, especially around gene expression, systemic repair, and anti-aging effects, haven't been confirmed in large-scale human studies
Typical Injection Schedules Most people fall into a predictable range once their levels are known
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