In addition to GLP-1 release, exposure to flagellin or lipopolysaccharide (85, 86) also results in expression of pro-inflammatory cytokines and evokes a gene response indicating EECs to participate in innate immune responses to commensals and pathogens (85)
Why it matters for weight loss: Without sufficient choline, fat accumulates in the liver instead of being exported and burned
This drug may cause side effects, including nausea/vomiting, diarrhea, constipation, abdominal pain, dyspepsia, injection site reactions, fatigue, hypersensitivity reactions, gas, hair loss, GERD, abdominal distension, dizziness, and low blood pressure
Retatrutide is a triple agonist for GLP-1, GIP, and glucagon receptors, which produces its superior weight loss results compared to single or dual agonists