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GLP-1 receptor agonists like Ozempic basically tell your stomach to slow down, which is great for blood sugar control and appetite, but leads to constipation, says Michael Bass, MD, a board-certified gastroenterologist and hepatologist and the founding medical director of Oshi Health

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That means we are, in many respects, working with incomplete data at exactly the moment when these medications are being prescribed at unprecedented scale

While probiotic supplements have a strong safety record (even at very high doses), you may be wondering if theyre to blame for your new symptoms