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AMPK antagonizes mammalian target of rapamycin (mTOR) activity, and its downstream effector, p27, inhibits cyclin-dependent kinase 2 (CDK2), thereby blocking the G1/S transition in the cell cycle, halting cell division, and subsequently inhibiting cellular proliferation [57]
Yes, studies suggest it is safe for long-term use, but ongoing monitoring is recommended
Understanding this timeline helps patients maintain realistic expectations and persist with therapy when clinically appropriate
These vitamins play vital roles in various bodily functions, and their deficiency can lead to health issues
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