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Reported effects include modulation of matrix metalloproteinase (MMP) expression and of tissue inhibitor of metalloproteinase (TIMP) expression in fibroblast culture, an anti-inflammatory profile in skin-irritation models, and in vitro effects on keratinocyte integrin and p63 expression collectively the fibroblast stimulation and matrix-remodeling signature that defines the molecules place in the skin-research literature (Pickart et al., 2015
Dubuquoy, C
However, it is mainly administered subcutaneously
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