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Metformin is a safe and healthy way to facilitate weight loss, even for patients without risk or incidence of type 2 diabetes

PIONEER 9 and 10 only included patients from Japan that had a lower average body weight, were mostly male (68% to 83% of patients) and were on a combination of background therapies that is atypical for patients living in Canada (high use of TZD and Alpha-glucosidase inhibitor in PIONEER 10)

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