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Furthermore, GLP-1R can also become internalized in response to GLP-1 and its analogs, indicating a complex regulatory mechanism that affects gene expression and protein activity [32]

A review of the effects of Garcinia cambogia suggested that taking it as a supplement may lower leptin levels (a hormone produced by fat cells that helps manage energy) as a result, but more research was needed

doi: 10.1152/ajpregu.00153.2008 97 PfefferMAClaggettBDiazRDicksteinKGersteinHCKberLVet al