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This work was supported by the China Postdoctoral Science Foundation (Grant #2022YFC3602300 and Grant #2024T171044), the Shenyang Public Health R&D Special Projects in 2022 (Project Grant #22-321-33-10), and the Scientific Research Fund Project of the Department of Education of Liaoning Province (Grant #JCZR2020005)

Significant Glucose Reduction: Evaluations of antidiabetic activity have shown that Moringa leaf extract significantly lowered blood glucose levels in diabetic rats, with effects comparable to insulin

The pathways of the oral microbiota causing APOs may be ( Porphyromonas gingivalis , the culprit of periodontitis, is a common anaerobic bacteria in the oral cavity and associated with many kinds of APOs, including fetal growth restriction ( Porphyromonas gingivalis causing APOs may be as follows: (1) Porphyromonas gingivalis directly invades the maternal tissue or placenta at the maternal-fetal interface ( Porphyromonas gingivalis evades the killing of the immune system by suppressing the immune response in the maternal tissues ( Porphyromonas gingivalis leads to increased inflammatory response in maternal and fetal tissues via regulating the immune response ( Porphyromonas gingivalis promotes the increase of acute-phase proteins in maternal and fetal tissues, such as alpha-fetoprotein and C-reactive protein ( Porphyromonas gingivalis promotes the invasion and colonization of other maternal microbes

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