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Regular exercise may help restore glutathione levels and improve antioxidant activities
Gradual dose titration, as recommended in prescribing guidelines, helps minimise these effects
However, 7 cross sectional studies examining acute effects of the GLP-1-based therapies 37,38,39,40,41,42,43 found a significant increase in % FMD following GLP-1-based interventions (mean difference in the changes from baseline: 2.58 [1.68, 3.53] %
Interestingly, emerging evidence suggests that GLP-1RAs may also provide therapeutic behavioral modification beyond their effects on appetite and food preferences
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