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Dihexa for Coeliac & Gluten Brain Fog The Yelland 2017 gluten-induced cognitive impairment review, the Lichtwark 2014 mucosal-healing cognition data, the Addolorato 2004 SPECT finding of reversible cerebral hypoperfusion in 73% of untreated coeliac patients, the Sheffield gluten-neurology / transglutaminase-6 tradition (Hadjivassiliou), NICE NG20, the malabsorption drivers, and Coeliac UKs ~1 in 100 / ~500,000-undiagnosed figures

ROS and RNS production in physiological conditions is maintained at low levels [25, 26] and used to regulate various physiological functions, including cell signaling, homeostasis, vascular tone, and immune reactions [27]

Rice D, Barone S (2000) Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models

Figure 3 4.1.1 Role of iron metabolism in ischemic stroke Prior to the formal identification of ferroptosis, studies had already linked iron accumulation to neuronal damage in both clinical settings and animal models of cerebral ischemia (35, 36, 131)