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GLOW is usually aligned with collagen and tissue remodeling research models, while KLOW is often chosen when researchers want broader pathway coverage that includes inflammation-response signaling (due to the inclusion of KPV)
However, there is little scientific evidence to support this claim
On the other hand, a highly significant increase ( p 0.001) was recorded in MDA level of MTX-treated rats compared with the control group
It is a useful marker when investigating oxidative stress or chronic illness, and as a baseline when tracking how an intervention shifts antioxidant status over time
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