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Switching between GLP-1 agonists may occasionally be considered if the reaction was mild and localised, as different formulations contain varying excipients

The FDA-approved Wegovy pill (oral semaglutide for weight management) is the same active ingredient as the Wegovy injection, formulated with a specialized absorption enhancer called SNAC (sodium N-[8-(2-hydroxybenzoyl)amino]caprylate) that allows enough semaglutide to cross the stomach lining to reach therapeutic blood levels