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An increased nuclear translocation of Nrf2, an induction of glutathione levels, and subsequent prevention of histological changes in the lens epithelial cells have been observed in rats treated with ferulic acid before and after ionizing radiation exposure
Although functional Seahorse assays clearly confirmed a role for MTP in mediating the ability to modulate cellular metabolism, we cannot exclude the possibility that GLP-1(2836) may also interact with other partner proteins to achieve its effects on cell metabolism and cytoprotection
Los mecanismos fisiolgicos incluyen : adaptacin metablica con reduccin del gasto energtico en reposo, cambios en las hormonas intestinales (GLP-1, PYY, grelina), y dilatacin gradual del reservorio gstrico que permite mayor ingesta calrica
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