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Selenium, as part of the active site in GPXs, is an essential micronutrient shown to reduce colon cancer incidence and preneoplastic aberrant crypt foci in animal models (27, 28, 29)
Thyroid function and nutritional markers TSH (thyroid stimulating hormone) monitoring is recommended for people on semaglutide, primarily because GLP-1 receptor agonists as a drug class have been associated with C-cell hyperplasia in animal studies, which raised theoretical concerns about thyroid cancer risk
[cited 2025 Nov 17]
GLP-1 also has beneficial effects on metabolism, helping the body use energy more efficiently
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