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FIGURE 5 In summary, metformin demonstrates limited efficacy in the prevention of EC associated with PCOS

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The main action of SOD is to reduce the damage caused by superoxide, the most common free radical, by converting superoxide into water and hydrogen peroxide

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The former involves conversion of tryptophan to 5-HT by tryptophan hydroxylase (TPH), followed by metabolism to 5-hydroxyindoleacetic acid (5-HIAA) via monoamine oxidase in blood

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