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Most Common Side Effects Dry mouth Insomnia or disrupted sleep Increased heart rate or blood pressure Mild nausea (typically dose-related and temporary) Restlessness or mild anxiety in sensitive individuals Adverse events were mostly mild to moderate and occurred during early weeks of treatment
MOTS-c is typically administered via subcutaneous injection into the abdomen, lateral thigh, or flank, rotating injection sites to prevent tissue accumulation
However, the drug raises hopes that the GLP-1 class of drugs more generally could help treat alcohol use disorder, which aligns well with recent data released in May from the Copenhagen University Hospital investigating semaglutide
Pilot trial (bladder pain): In 2024, a private clinic published a pilot study treating 12 women with severe interstitial cystitis (bladder pain syndrome) by injecting 10 mg of BPC-157 into the bladder wall (urotoday.com)
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